Product overview:

HNRNPM mouse monoclonal antibody, clone LBI4C9

Field of research:

Spliceosome

Summary:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug

Alternative names:

CEAR; hnRNP M; HNRNPM4; HNRPM; HNRPM4; HTGR1; NAGR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HNRNPM

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-261 of human HNRNPM (NP_112480) produced in E.coli.

Clone:

LBI4C9

Conjugation:

Unconjugated

Gene name:

heterogeneous nuclear ribonucleoprotein M

Symbol:

HNRNPM

Pathway:

Spliceosome

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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