Product overview:

RORA mouse monoclonal antibody, clone LBI2E8

Field of research:

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Summary:

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RORA

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 98-345 of human RORA (NP_002934) produced in E.coli.

Clone:

LBI2E8

Conjugation:

Unconjugated

Gene name:

RAR related orphan receptor A

Symbol:

RORA

Pathway:

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Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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