Product overview:

EZH2 mouse monoclonal antibody, clone LBI10B10

Field of research:

Request info at info@sobekbio.com

Summary:

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Alternative names:

ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

EZH2

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.

Clone:

LBI10B10

Conjugation:

Unconjugated

Gene name:

enhancer of zeste 2 polycomb repressive complex 2 subunit

Symbol:

EZH2

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com