Product overview:

HMBS mouse monoclonal antibody, clone LBI5B11

Field of research:

Metabolic pathways, Porphyrin and chlorophyll metabolism

Summary:

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Alternative names:

PBG-D; PBGD; PORC; UPS

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HMBS

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.

Clone:

LBI5B11

Conjugation:

Unconjugated

Gene name:

hydroxymethylbilane synthase

Symbol:

HMBS

Pathway:

Metabolic pathways, Porphyrin and chlorophyll metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com