Product overview:

OTC mouse monoclonal antibody, clone LBI2C2

Field of research:

Arginine and proline metabolism, Metabolic pathways

Summary:

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008]

Alternative names:

OCTD; OTCD

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

OTC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 33-354 of human OTC (NP_000522)produced in SF9 cell.

Clone:

LBI2C2

Conjugation:

Unconjugated

Gene name:

ornithine carbamoyltransferase

Symbol:

OTC

Pathway:

Arginine and proline metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com