Product overview:

STK11 mouse monoclonal antibody, clone LBI0A3

Field of research:

Adipocytokine signaling pathway, mTOR signaling pathway

Summary:

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Alternative names:

hLKB1; LKB1; PJS

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

STK11

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-236 of human STK11 (NP_000446) produced in E.coli.

Clone:

LBI0A3

Conjugation:

Unconjugated

Gene name:

serine/threonine kinase 11

Symbol:

STK11

Pathway:

Adipocytokine signaling pathway, mTOR signaling pathway

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com