Product overview:

DOT1L mouse monoclonal antibody, clone LBI1F8

Field of research:

Lysine degradation

Summary:

The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]

Alternative names:

DOT1; KMT4

Species reactivity:

Human

Host:

Mouse

Target:

DOT1L

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-434 of human DOT1L (NP_115871) produced in E.coli.

Clone:

LBI1F8

Conjugation:

Unconjugated

Gene name:

DOT1 like histone lysine methyltransferase

Symbol:

DOT1L

Pathway:

Lysine degradation

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com