Product overview:

ASL mouse monoclonal antibody, clone LBI3D4

Field of research:

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Summary:

This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul

Alternative names:

ASAL

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ASL

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human ASL (NP_001020114) produced in HEK293T cell.

Clone:

LBI3D4

Conjugation:

Unconjugated

Gene name:

argininosuccinate lyase

Symbol:

ASL

Pathway:

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com