Product overview:

KLK2 mouse monoclonal antibody, clone LBI5D6

Field of research:

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Summary:

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]

Alternative names:

hGK-1; hK2; KLK2A2

Species reactivity:

Human

Host:

Mouse

Target:

KLK2

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 25-261 of human KLK2 (NP_005542) produced in SF9 cell.

Clone:

LBI5D6

Conjugation:

Unconjugated

Gene name:

kallikrein related peptidase 2

Symbol:

KLK2

Pathway:

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Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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