Product overview:

EPAS1 mouse monoclonal antibody, clone LBI2A6

Field of research:

Pathways in cancer, Renal cell carcinoma

Summary:

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

Alternative names:

bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

EPAS1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 584-870 of human EPAS1 (NP_001421) produced in E.coli.

Clone:

LBI2A6

Conjugation:

Unconjugated

Gene name:

endothelial PAS domain protein 1

Symbol:

EPAS1

Pathway:

Pathways in cancer, Renal cell carcinoma

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com