Product overview:

TNFRSF9 mouse monoclonal antibody,clone LBI5H5

Field of research:

Cytokine-cytokine receptor interaction

Summary:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

Alternative names:

4-1BB; CD137; CDw137; ILA

Species reactivity:

Human

Host:

Mouse

Target:

TNFRSF9

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 24-186 of human TNFRSF9 (NP_001552) produced in E.coli.

Clone:

LBI5H5

Conjugation:

Unconjugated

Gene name:

tumor necrosis factor receptor superfamily member 9

Symbol:

TNFRSF9

Pathway:

Cytokine-cytokine receptor interaction

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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