Product overview:

LGALS3 mouse monoclonal antibody, clone LBI1C7

Field of research:

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Summary:

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Alternative names:

CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

LGALS3

Isotype:

IgG

Immunogen:

Full length human recombinant protein of human LGALS3 (NP_002297) produced in E.coli.

Clone:

LBI1C7

Conjugation:

Unconjugated

Gene name:

lectin, galactoside binding soluble 3

Symbol:

LGALS3

Pathway:

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Function:

Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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