Product overview:

KLK8 mouse monoclonal antibody, clone LBI4C12

Field of research:

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Summary:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq, Jul

Alternative names:

HNP; NP; NRPN; PRSS19; TADG14

Species reactivity:

Human

Host:

Mouse

Target:

KLK8

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 33-260 of human KLK8 (NP_009127) produced in E.coli.

Clone:

LBI4C12

Conjugation:

Unconjugated

Gene name:

kallikrein related peptidase 8

Symbol:

KLK8

Pathway:

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Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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