Product overview:

NME1 mouse monoclonal antibody, clone LBI6E9

Field of research:

Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Summary:

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

Alternative names:

AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NME1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human NME1 (NP_937818) produced in E.coli.

Clone:

LBI6E9

Conjugation:

Unconjugated

Gene name:

NME/NM23 nucleoside diphosphate kinase 1

Symbol:

NME1

Pathway:

Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com