Product overview:

WFDC2 (HE4) mouse monoclonal antibody, clone LBI3A9

Field of research:

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Summary:

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]

Alternative names:

dJ461P17.6; EDDM4; HE4; WAP5

Species reactivity:

Human

Host:

Mouse

Target:

WFDC2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 31-124 of human WFDC2 (NP_006094) produced in E.coli.

Clone:

LBI3A9

Conjugation:

Unconjugated

Gene name:

WAP four-disulfide core domain 2

Symbol:

WFDC2

Pathway:

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Function:

Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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