Product overview:

ESR2 mouse monoclonal antibody,clone LBI2E12

Field of research:

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Summary:

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Alternative names:

ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ESR2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-260 of human ESR2 (NP_001428) produced in E.coli.

Clone:

LBI2E12

Conjugation:

Unconjugated

Gene name:

estrogen receptor 2

Symbol:

ESR2

Pathway:

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Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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