Product overview:

TYMP (Thymidine Phosphorylase) mouse monoclonal antibody, clone LBI1E7

Field of research:

Bladder cancer, Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Summary:

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Alternative names:

ECGF; ECGF1; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; TP

Species reactivity:

Human

Host:

Mouse

Target:

TYMP

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 311-482 of human TYMP (NP_001944) produced in E.coli.

Clone:

LBI1E7

Conjugation:

Unconjugated

Gene name:

thymidine phosphorylase

Symbol:

TYMP

Pathway:

Bladder cancer, Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com