Product overview:

CD99 mouse monoclonal antibody, clone LBI1E12

Field of research:

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Summary:

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

HBA71; MIC2; MIC2X; MIC2Y; MSK5X

Species reactivity:

Human

Host:

Mouse

Target:

CD99

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CD99 (NP_002405) produced in HEK293T cell.

Clone:

LBI1E12

Conjugation:

Unconjugated

Gene name:

CD99 molecule

Symbol:

CD99

Pathway:

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com