Product overview:

HOXD10 mouse monoclonal antibody,clone LBI1D11

Field of research:

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Summary:

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul

Alternative names:

Hox-4.4; HOX4; HOX4D; HOX4E

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HOXD10

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 80-340 of human HOXD10 (NP_002139) produced in E.coli.

Clone:

LBI1D11

Conjugation:

Unconjugated

Gene name:

homeobox D10

Symbol:

HOXD10

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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