Product overview:

LNX1 mouse monoclonal antibody, clone LBI1H9

Field of research:

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Summary:

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

LNX; MPDZ; PDZRN2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

LNX1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 260-528 of human LNX1 (NP_116011) produced in E.coli.

Clone:

LBI1H9

Conjugation:

Unconjugated

Gene name:

ligand of numb-protein X 1

Symbol:

LNX1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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