Product overview:

KRT5 (Keratin 5) mouse monoclonal antibody, clone LBI1C7

Field of research:

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Summary:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Alternative names:

CK5; DDD; DDD1; EBS2; K5; KRT5A

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KRT5

Isotype:

IgG1

Immunogen:

Synthetic peptide: EQGTKTVRQN LEPLFEQYIN NLRRQ, corresponding to the conserved region of human KRT5 and KRT6

Clone:

LBI1C7

Conjugation:

Unconjugated

Gene name:

keratin 5

Symbol:

KRT5

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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