Product overview:

TIA1 mouse monoclonal antibody, clone LBI1A3

Field of research:

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Summary:

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]

Alternative names:

ALS26; TIA-1; WDM

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TIA1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TIA1 (NP_071505) produced in HEK293T cell.

Clone:

LBI1A3

Conjugation:

Unconjugated

Gene name:

TIA1 cytotoxic granule-associated RNA binding protein

Symbol:

TIA1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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