Product overview:

PPT1 mouse monoclonal antibody, clone LBI1F10

Field of research:

Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways

Summary:

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Alternative names:

CLN1; INCL; PPT

Species reactivity:

Human

Host:

Mouse

Target:

PPT1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 100-306 of human PPT1 (NP_000301) produced in E.coli.

Clone:

LBI1F10

Conjugation:

Unconjugated

Gene name:

palmitoyl-protein thioesterase 1

Symbol:

PPT1

Pathway:

Fatty acid elongation in mitochondria, Lysosome, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com