Product overview:

MMADHC mouse monoclonal antibody, clone LBI1G4

Field of research:

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Summary:

This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X. [provided by RefSeq, Nov

Alternative names:

C2orf25; cblD; CL25022

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

MMADHC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 39-296 of human MMADHC (NP_056517) produced in E.coli.

Clone:

LBI1G4

Conjugation:

Unconjugated

Gene name:

methylmalonic aciduria and homocystinuria, cblD type

Symbol:

MMADHC

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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