Product overview:

HBS1L mouse monoclonal antibody, clone LBI1C1

Field of research:

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Summary:

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

EF-1a; eRF3c; ERFS; HBS1; HSPC276

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HBS1L

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-260 of human HBS1L (NP_006611) produced in E.coli.

Clone:

LBI1C1

Conjugation:

Unconjugated

Gene name:

HBS1 like translational GTPase

Symbol:

HBS1L

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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