Product overview:

OSBPL2 mouse monoclonal antibody, clone LBI2E6

Field of research:

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Summary:

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Alternative names:

DFNA67; DNFA67; ORP-2; ORP2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

OSBPL2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 258-480 of human OSBPL2 (NP_653081) produced in E.coli.

Clone:

LBI2E6

Conjugation:

Unconjugated

Gene name:

oxysterol binding protein like 2

Symbol:

OSBPL2

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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