Product overview:

CUL4B mouse monoclonal antibody, clone LBI1C4

Field of research:

Nucleotide excision repair, Ubiquitin mediated proteolysis

Summary:

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

CUL4B

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.

Clone:

LBI1C4

Conjugation:

Unconjugated

Gene name:

cullin 4B

Symbol:

CUL4B

Pathway:

Nucleotide excision repair, Ubiquitin mediated proteolysis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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