Product overview:

EPHX1 (Epoxide Hydrolase 1) mouse monoclonal antibody, clone LBI3F10

Field of research:

Metabolism of xenobiotics by cytochrome P450

Summary:

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2008]

Alternative names:

EPHX; EPOX; HYL1; MEH

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

EPHX1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 21-230 of human EPHX1 (NP_000111) produced in E.coli.

Clone:

LBI3F10

Conjugation:

Unconjugated

Gene name:

epoxide hydrolase 1

Symbol:

EPHX1

Pathway:

Metabolism of xenobiotics by cytochrome P450

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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