Product overview:

PSMA6 (Proteasome 20S alpha 6) mouse monoclonal antibody, clone LBI7C2

Field of research:

Proteasome

Summary:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]

Alternative names:

IOTA; p27K; PROS27

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

PSMA6

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.

Clone:

LBI7C2

Conjugation:

Unconjugated

Gene name:

proteasome subunit alpha 6

Symbol:

PSMA6

Pathway:

Proteasome

Function:

Druggable Genome, Protease, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com