Product overview:

MADCAM1 mouse monoclonal antibody, clone LBI1A5

Field of research:

Cell adhesion molecules (CAMs)

Summary:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Alternative names:

MACAM1

Species reactivity:

Human

Host:

Mouse

Target:

MADCAM1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human MADCAM1(NP_570116) produced in HEK293T cell.

Clone:

LBI1A5

Conjugation:

Unconjugated

Gene name:

mucosal vascular addressin cell adhesion molecule 1

Symbol:

MADCAM1

Pathway:

Cell adhesion molecules (CAMs)

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com