Product overview:

RAPGEF1 mouse monoclonal antibody, clone LBI2B5

Field of research:

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Summary:

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Alternative names:

C3G; GRF2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RAPGEF1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human RAPGEF1(NP_941372) produced in HEK293T cell.

Clone:

LBI2B5

Conjugation:

Unconjugated

Gene name:

Rap guanine nucleotide exchange factor 1

Symbol:

RAPGEF1

Pathway:

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IHC: 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com