Product overview:

CSH1 mouse monoclonal antibody, clone LBI4D6

Field of research:

Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction

Summary:

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]

Alternative names:

CS-1; CSA; CSMT; GHB3; PL; hCS-1; hCS-A

Species reactivity:

Human

Host:

Mouse

Target:

CSH1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CSH1(NP_072166) produced in HEK293T cell.

Clone:

LBI4D6

Conjugation:

Unconjugated

Gene name:

chorionic somatomammotropin hormone 1

Symbol:

CSH1

Pathway:

Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com