Product overview:

PMS2 mouse monoclonal antibody, clone LBI4B7

Field of research:

Mismatch repair

Summary:

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

HNPCC4; MLH4; PMS2CL; PMSL2

Species reactivity:

Human

Host:

Mouse

Target:

PMS2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.

Clone:

LBI4B7

Conjugation:

Unconjugated

Gene name:

PMS1 homolog 2, mismatch repair system component

Symbol:

PMS2

Pathway:

Mismatch repair

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150, IF: 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com