Product overview:

TH mouse monoclonal antibody, clone LBI2E5

Field of research:

Metabolic pathways, Parkinson's disease, Tyrosine metabolism

Summary:

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

DYT5b; DYT14; TYH

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TH

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TH(NP_000351) produced in HEK293T cell.

Clone:

LBI2E5

Conjugation:

Unconjugated

Gene name:

tyrosine hydroxylase

Symbol:

TH

Pathway:

Metabolic pathways, Parkinson's disease, Tyrosine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IF 1:100, IHC: 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com