Product overview:

CDH3 (P cadherin) mouse monoclonal antibody, clone LBI2D5

Field of research:

Cell adhesion molecules (CAMs)

Summary:

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]

Alternative names:

CDHP; HJMD; PCAD

Species reactivity:

Human

Host:

Mouse

Target:

CDH3

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.

Clone:

LBI2D5

Conjugation:

Unconjugated

Gene name:

cadherin 3

Symbol:

CDH3

Pathway:

Cell adhesion molecules (CAMs)

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com