Product overview:

Carrier-free (BSA/glycerol-free) ISL1 mouse monoclonal antibody, clone LBI2D8

Field of research:

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Summary:

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

Alternative names:

Isl-1; ISLET1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ISL1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 134-349 of human ISL1(NP_002193) produced in E.coli.

Clone:

LBI2D8

Conjugation:

Unconjugated

Gene name:

Homo sapiens ISL LIM homeobox 1 (ISL1), mRNA.

Symbol:

ISL1

Pathway:

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Function:

ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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