Product overview:

Carrier-free (BSA/glycerol-free) TRIB3 mouse monoclonal antibody, clone LBI2D11

Field of research:

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Summary:

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

Alternative names:

C20orf97; NIPK; SINK; SKIP3; TRB3

Species reactivity:

Human

Host:

Mouse

Target:

TRIB3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-200 of human TRIB3(NP_066981) produced in E.coli.

Clone:

LBI2D11

Conjugation:

Unconjugated

Gene name:

Homo sapiens tribbles pseudokinase 3 (TRIB3), transcript variant 1, also known as 1A, mRNA.

Symbol:

TRIB3

Pathway:

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Function:

Druggable Genome, Protein Kinase, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com