Product overview:

Carrier-free (BSA/glycerol-free) PAPSS2 mouse monoclonal antibody, clone LBI1E12

Field of research:

Metabolic pathways, Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism

Summary:

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

ATPSK2; BCYM4; SK2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PAPSS2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-247 of human PAPSS2(NP_004661) produced in E.coli.

Clone:

LBI1E12

Conjugation:

Unconjugated

Gene name:

Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2), transcript variant 1, mRNA.

Symbol:

PAPSS2

Pathway:

Metabolic pathways, Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com