Product overview:

Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody, clone LBI14B3

Field of research:

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Summary:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Alternative names:

CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2

Species reactivity:

Human

Host:

Mouse

Target:

PDCD1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.

Clone:

LBI14B3

Conjugation:

Unconjugated

Gene name:

Homo sapiens programmed cell death 1 (PDCD1), mRNA.

Symbol:

PDCD1

Pathway:

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100~900, FLOW 1:50

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com