Product overview:

Carrier-free (BSA/glycerol-free) FLT1 mouse monoclonal antibody, clone LBI8G6

Field of research:

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

Summary:

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. [provided by RefSeq, May 2009]

Alternative names:

FLT; FLT-1; VEGFR-1; VEGFR1

Species reactivity:

Human

Host:

Mouse

Target:

FLT1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 781-1338 of human FLT1 (NP_002010) produced in HEK293T cell.

Clone:

LBI8G6

Conjugation:

Unconjugated

Gene name:

Homo sapiens fms related receptor tyrosine kinase 1 (FLT1), transcript variant 1, mRNA.

Symbol:

FLT1

Pathway:

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

Function:

Druggable Genome, Protein Kinase, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com