Product overview:

Carrier-free (BSA/glycerol-free) RHOC mouse monoclonal antibody, clone LBI6F11

Field of research:

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Summary:

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Alternative names:

ARH9; ARHC; H9; RHOH9

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RHOC

Isotype:

IgG1

Immunogen:

Synthetic peptide: VFEMATRAGLQVRKNKRRRG, corresponding to C terminal of human RHOC.

Clone:

LBI6F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens ras homolog family member C (RHOC), transcript variant 1, mRNA.

Symbol:

RHOC

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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