Product overview:

Carrier-free (BSA/glycerol-free) GEMIN8 mouse monoclonal antibody, clone LBI4F8

Field of research:

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Summary:

The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Alternative names:

FAM51A1

Species reactivity:

Human

Host:

Mouse

Target:

GEMIN8

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human GEMIN8 (NP_060326) produced in E.coli.

Clone:

LBI4F8

Conjugation:

Unconjugated

Gene name:

Homo sapiens gem nuclear organelle associated protein 8 (GEMIN8), transcript variant 3, mRNA.

Symbol:

GEMIN8

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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