Product overview:

Carrier-free (BSA/glycerol-free) ROS1 mouse monoclonal antibody, clone LBI1F3

Field of research:

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Summary:

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

Alternative names:

c-ros-1; MCF3; ROS

Species reactivity:

Human

Host:

Mouse

Target:

ROS1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 2126-2347 of human ROS1(NP_002935) produced in E.coli.

Clone:

LBI1F3

Conjugation:

Unconjugated

Gene name:

Homo sapiens ROS proto-oncogene 1, receptor tyrosine kinase (ROS1), transcript variant 1, mRNA.

Symbol:

ROS1

Pathway:

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Function:

Druggable Genome, Protein Kinase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:5000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com