Product overview:

Carrier-free (BSA/glycerol-free) MSLN mouse monoclonal antibody, clone LBI8H7

Field of research:

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Summary:

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Alternative names:

MPF; SMRP

Species reactivity:

Human

Host:

Mouse

Target:

MSLN

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 270-493 of human MSLN (NP_005814) produced in E.coli.

Clone:

LBI8H7

Conjugation:

Unconjugated

Gene name:

Homo sapiens mesothelin (MSLN), transcript variant 1, mRNA.

Symbol:

MSLN

Pathway:

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Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com