Product overview:

Carrier-free (BSA/glycerol-free) MKL1 mouse monoclonal antibody, clone LBI2B3

Field of research:

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Summary:

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Alternative names:

BSAC; MAL; MRTF-A

Species reactivity:

Human

Host:

Mouse

Target:

MRTFA

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1 (NP_065882) produced in E.coli.

Clone:

LBI2B3

Conjugation:

Unconjugated

Gene name:

Homo sapiens myocardin related transcription factor A (MRTFA), transcript variant 1, mRNA.

Symbol:

MRTFA

Pathway:

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Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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