Product overview:

Carrier-free (BSA/glycerol-free) HDAC4 mouse monoclonal antibody, clone LBI6E6

Field of research:

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Summary:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Alternative names:

AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HDAC4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HDAC4 (NP_006028) produced in HEK293T cell.

Clone:

LBI6E6

Conjugation:

Unconjugated

Gene name:

Homo sapiens histone deacetylase 4 (HDAC4), transcript variant 2, mRNA.

Symbol:

HDAC4

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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