Product overview:

Carrier-free (BSA/glycerol-free) NR4A3 mouse monoclonal antibody, clone LBI1C1

Field of research:

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Summary:

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Alternative names:

CHN; CSMF; MINOR; NOR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NR4A3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 332-626 of human NR4A3 (NP_008912) produced in E.coli.

Clone:

LBI1C1

Conjugation:

Unconjugated

Gene name:

Homo sapiens nuclear receptor subfamily 4 group A member 3 (NR4A3), transcript variant 1, mRNA.

Symbol:

NR4A3

Pathway:

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Function:

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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