Product overview:

Carrier-free (BSA/glycerol-free) PTCH2 mouse monoclonal antibody, clone LBI1F5

Field of research:

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Summary:

This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Alternative names:

PTC2

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

PTCH2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 79-392 of human PTCH2 (NP_003729) produced in E.coli.

Clone:

LBI1F5

Conjugation:

Unconjugated

Gene name:

Homo sapiens patched 2 (PTCH2), transcript variant 1, mRNA.

Symbol:

PTCH2

Pathway:

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Function:

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com