Product overview:

Carrier-free (glycerol/BSA-free) SGK196 mouse monoclonal antibody, clone LBI2B6

Field of research:

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Summary:

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Alternative names:

MDDGA12; MDDGC12; SGK196

Species reactivity:

Human

Host:

Mouse

Target:

POMK

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 141-350 of human SGK196 (NP_115613) produced in E.coli.

Clone:

LBI2B6

Conjugation:

Unconjugated

Gene name:

Homo sapiens protein O-mannose kinase (POMK), transcript variant 1, mRNA.

Symbol:

POMK

Pathway:

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Function:

Druggable Genome, Protein Kinase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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