NIPP1 (PPP1R8) Mouse Monoclonal Antibody [Clone ID: LBI1E2] AMM16535VCF
Product overview:
Carrier-free (BSA/glycerol-free) PPP1R8 mouse monoclonal antibody, clone LBI1E2
Field of research:
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Summary:
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul
Alternative names:
ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Species reactivity:
Human, Mouse, Rat
Host:
Mouse
Target:
PPP1R8
Isotype:
IgG1
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-225 of human PPP1R8 (NP_612568) produced in E.coli.
Clone:
LBI1E2
Conjugation:
Unconjugated
Gene name:
Homo sapiens protein phosphatase 1 regulatory subunit 8 (PPP1R8), transcript variant 2, mRNA.
Symbol:
PPP1R8
Pathway:
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Function:
Druggable Genome, Transcription Factors
Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Concentration:
Form:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Applications & dilution:
WB 1:2000
Storage buffer:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage:
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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